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SlideshowReport

Initiation of a new round of replication before completion of the preceding round

Description
Labeling with [3H]-thymidine was started when the first round of replication began.

The pattern of grain density shows that one of the reinitiated branches contains two labeled strands, while the other contains only one.

Solid lines denote radiolabeled DNA, and dashed lines denote unlabeled DNA. Black arrowheads depict first-generation replication forks, and blue arrowheads depict second-generation replication forks.
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