Top Posters
Since Sunday
I
3
3
p
2
w
2
y
2
J
2
Q
2
r
2
o
2
e
2
j
2
d
2
SlideshowReport

Transport of newly synthesized mitochondrial proteins into the matrix

Description
Upper left, signal sequence of Hsp70-bound protein inserts into import receptor of the TOM complex (TOM20) in the outer membrane.
Hsp70 dissociation is coupled to ATP hydrolysis.
Insertion of the protein into the outer membrane (via TOM22) puts signal sequence in position to interact with TIM complex (TIM23) in the inner membrane.
Potential across the inner membrane drives protein into intermembrane space.
Signal sequence is cleaved off by MPP.
Mitochondrial Hsp70 binds to protein in the matrix and uses the energy of ATP hydrolysis to pull the rest of the protein through.
Related Images
Add Comment
Explore
Post your homework questions and get free online help from our incredible volunteers
  539 People Browsing
Show Emoticons
:):(;):P:D:|:O:?:nerd:8o:glasses::-):-(:-*O:-D>:-D:o):idea::important::help::error::warning::favorite:
Your Opinion
Who will win the 2024 president election?
Votes: 119
Closes: November 4