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Hemophilia A in Descendents of Queen Victoria of England

Description
A classic case of X-linked recessive inheritance: a partial pedigree of the descendants of Queen Victoria of England. At one time, the recessive X-linked allele that resulted in hemophilia was present in eighteen of Victoria’s sixty-nine descendants, who sometimes intermarried. Of the Russian royal family members shown, the mother (Alexandra Czarina Nicolas II) was a carrier.
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