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SlideshowReport

Relaxed and supercoiled DNA molecules

Description
Secondary and Tertiary Structure of Nucleic Acids

Electron micrograph showing three human mitochondrial DNA molecules.

All three are of identical sequence and contain 16,569 bp each.

However, the molecule in the center is relaxed, whereas those at top and bottom are tightly supercoiled.

Most DNA molecules found in vivo are
   left-handed supercoils.
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