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SlideshowReport

Validation of the genetic code by amino acid sequence analysis of T4 phage lysozyme mutants

Description
e is the gene for lysozyme, a portion of whose amino acid sequence is shown.

One of two proflavin-induced mutations, either eJ42 or eJ44 disrupted the reading frame by deleting one base pair, and a second mutation restored the wild-type reading frame by inserting a base pair, but altering the amino acid sequence between the two mutant sites.

The mRNA sequences encoding these five altered amino acids are inferred from the genetic code and the known action of the mutagen.
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