Partial map of disease genes on human chromosome 21

(b) Chromosome 21 50 million bases Coxsackie and adenovirus receptor Amyloidosis cerebroarterial, Dutch type Alzheimer disease, APP-related Schizophrenia, chronic Usher syndrome, autosomal recessive Amyotrophic lateral sclerosis Oligomycin sensitivity Jervell and Lange—Nielsen syndrome Long QT syndrome Down syndrome cell-adhesion molecule Homocystinuria Cataract, congenital, autosomal dominant Deafness, autosomal recessive Myxovirus (influenza) resistance Leukemia, acute myeloid in I II In M II Myeloproliferative syndrome, transient Leukemia transient of Down syndrome Enterokinase deficiency Multiple carboxylase deficiency T-cell lymphoma invasion and metastasis Mycobacterial infection, atypical Down syndrome (critical region) Autoimmune polyglandular disease, type 1 Bethlem myopathy Epilepsy, progressive myoclonic Holoprosencephaly, alobar Knobloch syndrome Hemolytic anemia Breast cancer Platelet disorder, with myeloid malignancy