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Risk of Down Syndrome (Trisomy 21) by Maternal Age

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Table 10.3 Risk of Down Syndrome (Trisomy 21) by Maternal Agea Maternal Age Range Total Live Births Studied Trisomy 21 Births Rate per 1000 Births 15—1 9 30,272 18 0.49 20—24 117,593 87 0.73 25—29 108,746 96 0.90 30—34 49,487 72 1 .56 35—39 19,522 73 4.19 40-44 4880 73 1 8.02 45—49 304 19 55.02 a Data adapted from E. B. Hook and A. Lindsjo, Down syndrome in live births by single year maternal age interval in a Swedish study: Comparison with results from a New York State study. Am. J. Hum. Genet. 30 (1978): 19—27.
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