Nucleosome inheritance after DNA replication

Following the passage of the replication fork, “old” H3–H4 tetramers are randomly assigned to daughter strands, and newly synthesized H3–H4 tetramers inhabit strands not bound by old tetramers. Old and new H2A–H2B dimers join the tetramers to form complete nucleosomes Following the passage of the replication fork, “old” H3–H4 tetramers are randomly assigned to daughter strands, and newly synthesized H3–H4 tetramers inhabit strands not bound by old tetramers. Old and new H2A–H2B dimers join the tetramers to form complete nucleosomes

(a) Nucleosome H3-H4 tetramer ‘v w.“ 9 1."! Parental nucleosome Direction of DNA replication Helicase "Old" H3—H4 “tram" ”Old" HZA and H23 proteins protein