A patient with a severe systemic fungal infection will be treated with amphotericin B (Fungizone). ...

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Rationale 1: This medication should be infused slowly to avoid cardiovascular collapse.
Rationale 2: Giving acetaminophen prior to the infusion may decrease risk of hypersensitivity reaction.
Rationale 3: The drug should be withheld if the BUN exceeds 40 g/dL.
Rationale 4: Corticosteroid administration should be part of pre-administration preparation.
Rationale 5: Gastrointestinal bleeding is not a concern.

Global Rationale: This medication should be infused slowly to avoid cardiovascular collapse. Giving acetaminophen prior to the infusion may decrease risk of hypersensitivity reaction. The drug should be withheld if the BUN exceeds 40 g/dL. Corticosteroid administration should be part of pre-administration preparation. Gastrointestinal bleeding is not a concern.