Stanleyblythe, so for the essay section are you saying that it is incomplete dominance that causes the purple color? Or is it due to the loss-of-function having leaky/hypomorphic mutations?
so for the essay section are you saying that it is incomplete dominance that causes the purple color? Or is it due to the loss-of-function having leaky/hypomorphic mutations?
I've figured it out guys.
A_bb (Red)
anything with aa: Turn (White)
A_BB Wild type (Blue)
A_Bb Turn (Purple)
The reason why it is because the genotype of their F1 generation: AaBb x AaBb
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So, for the essay section are you saying that it is incomplete dominance that causes the purple color? Or is it due to the loss-of-function having leaky/hypomorphic mutations?
Ohhhh my god, I've been working on this for hours but I think I've got it guys.
So the Purple and Blue colored bugs share what would be the 9 part of the 9:3:4 ratio that's in recessive epistasis so the F2 generation goes as follows:
AABB(b) AABb(p) AaBB(b) AaBb(p)
AABb(p) AAbb(w) AaBb(p) Aabb(w)
AaBB(b) AaBb(p) aaBB(r) aaBb(r)
AaBb(p) Aabb(w) aaBb(r) aabb(w)
so the p,b,r,w stand for the color
- anything with a "bb" will have the white color, there's four of them so that makes sense
- anything with an "aa" will be red, there's only three of them
- the purple color will only show up if there's a "AaBb" genotype, there's six
- and the blue color will only show up if there's a "A_BB" genotype, it wont matter if the second "a" is big or small (as long as one of them is a big A) the dominant "B's" will over power whatever the "A's" are, so there's 3 blue bugs
And I guess the loss of function comes into play where the little "b" in the AaBb (purple) genotype makes the blue coloration in the Blue wild type bug less prominent.
Let me know if this makes sense!
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What are you saying for the essay section: "Identify the dominance relationships between the wild-type alleles and the associated loss-of-function mutations. Explain how the pathway and the dominance relationships produce the 6:3:3:4 F2 ratios"
I'm thinking that the wild-type allele, B, is dominant. However, the presence of the recessive mutation allele, b, makes the wild-type allele less efficient. This would be due to a leaky/hypomorphic type of loss of mutation. Because of this, even though the purple flowers have the dominant wild-type allele, B, the phenotypic blue color would not be as prominent.