Advantages of small-volume ultrasonic nebulizers for drug delivery include which of the follow-ing? 1. Greater respirable drug mass 2. Less dead space and waste 3. Increased mobility 4. Decreased cost
a. 1 and 3 only
b. 1, 2, and 3 only
c. 3 and 4 only
d. 2, 3, and 4 only
Q. 2 Which of the following are true about a solution that is being aerosolized by an ultrasonic nebu-lizer?
1. The solute concentration decreases.
2. The temperature of the solution increases.
3. The solute concentration increases.
4. The temperature of the solution decreases.
a. 1 and 2 only
b. 2 and 3 only
c. 2 and 4 only
d. 3 and 4 only
Q. 3 What is the average mean mass aerodynamic diameter (MMAD) generated by the vibrating mesh nebulizers?
a. 1 to 2 m
b. 2 to 3 m
c. 3 to 4 m
d. 5 to 6 m
Q. 4 A physician has ordered the antiviral agent ribavirin (Virazole) to be administered by aerosol to an infant with bronchiolitis. Which of the following devices would you recommend in this situa-tion?
a. Hydrodynamic (Babbington) nebulizer
b. Small-particle aerosol generator (SPAG)
c. Ultrasonic (piezoelectric) nebulizer
d. Large-volume heated jet nebulizer
Q. 5 The small-particle aerosol generator (SPAG) produces a small monodisperse aerosol through which of the following?
a. Aerosol impaction by sequential baffling
b. Particle evaporation in a glass drying chamber
c. Use of an inert liquefied gas propellant
d. Aerosol generation using vibrational ener-gy
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