Advantages of the dry powder inhaler (DPI) drug delivery systems include which of the follow-ing?
1. Low relative cost
2. No propellants required
3. No hand-breath coordination necessary
4. Unaffected by humidity
a. 1 and 3 only
b. 1, 2, and 3 only
c. 3 and 4 only
d. 2, 3, and 4 only
Q. 2 Proper use of a dry powder inhaler (DPI) requires that the patient be able to do which of the fol-lowing?
a. Generate inspiratory flows of 60 L/min or higher.
b. Exhale forcibly through the device before drug delivery.
c. Inhale slowly (<0.5 L/sec) and perform a breath-hold.
d. Coordinate firing of the DPI with inspira-tion.
Q. 3 After actuating a metered dose inhaler with a holding chamber, what should the patient be in-structed to do?
a. Take a large breath and hold it for at least 5 sec.
b. Continue to breathe through the device for three breaths.
c. Immediately exhale as fast and as much as possible.
d. Take one quick breath and remove the holding chamber.
Q. 4 Which of the following are beneficial effects of using a holding chamber with a metered dose inhaler (MDI)?
1. Reduction in oropharyngeal aerosol deposition
2. Decrease in need for hand-breath coordination
3. Elimination of medication waste
a. 1 and 2 only
b. 1 and 3 only
c. 2 and 3 only
d. 1, 2, and 3
Q. 5 The key difference between a metered dose inhaler (MDI) holding chamber and a spacer is that the holding chamber incorporates which of the following?
a. Larger enclosed space
b. One-way inspiratory valve
c. Heated chamber
d. Series of baffles
Q. 6 Which of the following agents has been associated with increased intraocular pressure?
a. Anticholinergics
b. Epinephrine
c. Beta-2 agonists
d. Antibiotics
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