A 51-year-old man is receiving his annual physical exam, and his care provider is explaining the ...

A 51-year-old man is receiving his annual physical exam, and his care provider is explaining the rationale for performing a digital rectal exam (DRE). Which of the following statements best captures the rationale for the procedure?
 
  A)
  DRE, combined with a measurement of prostate-specific antigen (PSA), is the easiest way to confirm or rule out benign prostatic hyperplasia (BPH).
  B)
  The presence of an enlarged prostate provides a definitive diagnosis of prostate cancer.
  C)
  If the prostate is hardened on examination, a biopsy is indicated for further investigation.
  D)
  DRE is a screening test recommended for men who are experiencing either reduced urine flow or pain on urination.