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Suppose you are a genetic counsellor, and a man and woman come to you with concerns that if they ...

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Suppose you are a genetic counsellor, and a man and woman come to you with concerns that if they ...

Suppose you are a genetic counsellor, and a man and woman come to you with concerns that if they have a child together, it could have hemophilia. Also suppose that the woman has an X-linked recessive form of hemophilia, but the man does NOT. Which of the following is the best advice you could give them?

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Each of their male offspring will have hemophilia, and each of their female offspring will have a 50% chance of having hemophilia.

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Each of their male offspring will have a 50% chance of having hemophilia; and while their female offspring should not have hemophilia, they will each have a 50% chance of being carriers.

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None of their offspring should have hemophilia, but each of their female offspring will be carriers for hemophilia.

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Each of their male offspring will have hemophilia; and while their female offspring should not have hemophilia, they will all be carriers.

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Biology: Exploring the Diversity of Life

Edition: 4^th

Authors: Russell, Hertz, McMillan, Fenton

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