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Home Q & A Board Biology-Related Homework Help Medicine
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oelara oelara
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6 years ago
A patient with erosive esophagitis is taking lansoprazole (Prevacid). The primary care NP performs a medication history and learns that the patient also takes digoxin. The NP should recommend:
 
  a. decreasing the dose of digoxin.
  b. obtaining a serum digoxin level.
  c. changing the PPI to omeprazole.
  d. increasing the dose of lansoprazole.
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#1
6 years ago
B
Because PPIs decrease gastric acid, they may interfere with the absorption of drugs that require absorption in an acid stomach, including digoxin. It may be necessary to increase the dose of digoxin but not before obtaining a serum digoxin level. All PPIs have this effect, so changing to another PPI would not solve the problem. Increasing the dose of lansoprazole would decrease the absorption of digoxin.
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