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What is the clinical effect of a local anesthetic drug solution with a higher pKa?

IRAM

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What is the clinical effect of a local anesthetic drug solution with a higher pKa?

What is the clinical effect of a local anesthetic drug solution with a higher pKa?

A) Increased base molecule concentration and thereby slower onset of anesthesia
B) Increased cation molecule concentration and thereby faster onset of anesthesia
C) Increased base molecule concentration and thereby faster onset of anesthesia
D) Decreased base molecule concentration thereby slower onset of anesthesia

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