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Home Q & A Board Biology-Related Homework Help General Biology
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Tonya Cummings Tonya Cummings
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4 years ago
In the whole-genome shotgun method, the genome is fragmented and individual fragments are sequenced. How do we determine the order of the nucleotides in the intact chromosome?


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The fragmentation is done in a very systematic way such that the physical arrangement of fragments is readily apparent.


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The sequences of the ends of the fragments overlap with the ends of other fragments.


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We supplement our information with data from a different technique to determine the final chromosome arrangement.


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DNA hybridization assays are conducted to determine the physical arrangement of the genes on the chromosome.
Textbook 
Biology: Exploring the Diversity of Life

Biology: Exploring the Diversity of Life


Edition: 4th
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flylegendsflylegends
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4 years ago
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Tonya Cummings Author
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4 years ago
This site is awesome
patyfeitosa
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Yesterday
Helped a lot
momochiime
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Smart ... Thanks!
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