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Home Q & A Board Biology-Related Homework Help Medicine Nursing and Clinical
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colleen colleen
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12 years ago
A child with a long history of repeated cases of strep throat develops a heart murmur. What is the most likely diagnosis, and what has caused this condition to develop?
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Sunshine ☀ ☼

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12 years ago
The child is most likely suffering from rheumatic fever. This is a complication of untreated type A streptococcal pharyngitis–that is, strep throat. The condition is not caused directly by streptococcus, but is actually an autoimmune response. Antibodies against the streptococcal antigen cross-react with heart antigens, leading to damage of the heart valves. Damage may be so extensive that the valves must be replaced when the patient reaches middle age.
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