Epidemiological study found that patent ductus arteriosus in patients with
PTPN2 unexplained Death ovale (PFO) incidence of 44-66%; death underwent autopsy, PFO incidence was 27%. PFO in the cryptogenic stroke population, suggesting that their stroke may be due to abnormalities of venous thromboembolism (PTEs). Percutaneous arterial catheter occlusion has been used in clinical than 10 years, but still the lack of strong evidence to help clinicians decide when and how the line of the ductus arteriosus closure block. Surrounding the PFO with PTPN4 unexplained stroke / TIA patients with optimal treatment strategies, and controversial.This study tries to line Meta-analysis, Comparison of patent foramen ovale (PFO) merger cryptogenic stroke / transient cerebral ischemia (TIA) has been observational study in patients with PTPN6 foramen ovale occluder in transcatheter and drug treatment recurrent neurological events after the incidence.
Research using standard search criteria to retrieve qualified literature on MEDLINE. Analysis of qualified literature data, the results are as follows:Recurrent neurological events after adjusting for the incidence for the transcatheter closure group and 0.8 events per 100 people (95% confidence interval 0.5 to 1.1), the drug treatment group, 5.0 events per year for every 100 people (95% confidence interval, 3.6 to 6.9). Catheter occlusion a small number of the PTPN7 Comparative Study of Meta-analysis and multiple regression analysis showed that, compared with drug treatment of recurrent neurological events in the prevention of cryptogenic stroke more. PTPN9 Drug treatment is divided into two subgroups, anticoagulant and antiplatelet therapy and found that the use of anticoagulant therapy in patients with RNE the risk of a significant reduction. Device-related complications was 4.1 per year per 100 people (95% confidence interval 3.2 to 5.0), of which the most common atrial tachycardia. OK after transcatheter closure of recurrent neurological events seemed to be nothing to do with the residual sub-flow sub-flow size or postoperative follow-up period before it is processed. Catheter occlusion, a significant advantage in the elderly, atrial septal aneurysm in patients with thrombophilia is more obvious.This meta-analysis, researchers concluded that:Ovale associated with cryptogenic stroke / TIA of arterial catheters in patients with catheter occlusion and the thickness of the drug treatment of recurrent neurological events of the incidence of 0.8 and 5.1 events per 100 people. Also need further study of these two treatment strategies do the final comparison.
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