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Babygal Babygal
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14 years ago Edited: 14 years ago, Princess
My question is:

Reciprocal translocations can be well tolerated. However, if the transocations placed gene A (whose transcription is tightly regulated) in front of a new promoter that is constitutive, what can one expect from this aberration?
YOU MUST ALSO EXPLAIN WHY YOU CHOSE YOUR ANSWER
a. Gene A will always be “off”
b. Gene A will always be “on”
c. The organism’s phenotype could be deleteriously affected.
d. There will be no effect on phenotype
e. b and c
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wrote...
14 years ago
Constitutive chromatin is always inactive, so the genes in it will never be transcribed.. if a gene A is placed in front of a promoter that is constitutive then it will also become inactive... so the answer would be " a ". But if this gene had a very important role then the organism's phenotype could also be deleteriously ( since a gene is lost ) affect. I don't know if you can put two answers.. and plz correct me if i'm wrong because i never came across something as " a promoter that is constitutive " so my analogy might be incorrect.
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