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Home Q & A Board Biology-Related Homework Help Anatomy and Physiology
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nite_n_day nite_n_day
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10 years ago
What role do hormones play in hunger and satiety?
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Eric Clapton
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10 years ago
"The two major hormones that control the hunger and satiety cells are ghrelin and leptin. Ghrelin is produced by the stomach and travels to the brain where it turns on the hunger cell and turns off the satiety cell. Leptin is produced by the fat cells of the body and travels to the brain where it turns on the satiety cell and turns off the hunger cell. When you are obese you have lots of fat cells and thus your leptin levels are high. The high leptin levels in combination with high insulin levels turn off the stomach cells that make ghrelin so your ghrelin levels are low. The problem is that high leptin levels over time make the satiety cell insensitive to leptin and low ghrelin levels make the hunger cell hypersensitive to ghrelin. The result is that even though the leptin levels are high and the ghrelin levels are low, the hunger cells are turned on and the satiety cells are turned off."
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nite_n_day Authornite_n_day
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10 years ago
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Would you know my name, if I saw you in heaven?

Eric Clapton

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10 years ago
Levels of ghrelin, a hormone produced by P/D1 cells, lining the fundic region of the stomach, rise before meals to initiate hunger and decline shortly after eating to curb appetite. Ghrelin is also antagonistic to leptin, a fat-tissue-derived hormone that induces satiety. Another hormone from the stomach and small intestine, obestatin, decreases appetite. The same gene encodes both ghrelin and obestatin.
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