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Home Q & A Board Science-Related Homework Help High School Level Science
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10 years ago
The royal family of Russia included Czar Nicholas II and his wife Alexandria; their daughters Olga, Maria,Tatiana and Anastasia; and their son Alexia Of the family members, only Alexis was a hemophiliac. Czar Nicholas II was not a hemophiliac. His wife, Alexandria, was a carrier for hemophilia. What was the probability that any of their daughters was a carrier for hemophilia?
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10 years ago
Given that hemophilia is typically X-linked, the genotypes of the parents are as follows:
Nicholas: XY (unaffected)
Alexandria XXA (carrier)

All of their male progeny would therefore be affected, and their female progeny would have a 50% chance of being a carrier (one unaffected X from Nicholas and a 50% chance of an unaffected X from Alexandria, and a 50% chance of an affected X from Alexandria).  Pedigree attached below:

Answer is 50%
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