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mooma mooma
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10 years ago
how do mutations shorten a protein such as BRCA 1 gene?
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Staff Member
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10 years ago
Nonsense mutation



In this example, the nucleotide cytosine is replaced by thymine in the DNA code, signaling the cell to shorten the protein.

A nonsense mutation is also a change in one DNA base pair. Instead of substituting one amino acid for another, however, the altered DNA sequence prematurely signals the cell to stop building a protein. This type of mutation results in a shortened protein that may function improperly or not at all.
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