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colleen colleen
wrote...
Valued Member
Posts: 17077
12 years ago
How would known cancer cells that possess multidrug resistance transport proteins affect cancer treatment? How might you potentially counter the effect of such transporters?
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Sunshine ☀ ☼

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wrote...
Educator
12 years ago
You should discuss the mechanism whereby the transporter removes the drug before it could potentially have an effect on the cancer cells. Further, they should hypothesize that treatments that prevent functioning of the MDR transport protein, such as monoclonal antibody binding of the transport protein or prior treatment of the cells with a competitive or noncompetitive inhibitor followed by drug treatment, are possible. Evaluate integrity of other possible answers.
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