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GPOWER GPOWER
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10 years ago
I was reading the following report about metabolism of hibernating squirrels and it says that while whole-animal metabolism falls(due to core temperature falling), mitochondrial metabolism stays stable...

How is that possible since biochemical reactions slow down while temperature falling? How can mitochondrial metabolism not be supressed?

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#1
10 years ago
During bouts of torpor, mitochondrial metabolism is known to be suppressed in the liver and skeletal muscle of hibernating mammals. This suppression is rapidly reversed during interbout euthermic (IBE) phases, when whole-animal metabolic rate and body temperature return spontaneously to euthermic levels.

Source  http://www.ncbi.nlm.nih.gov/pubmed/23303316
GPOWER Author
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#2
10 years ago
These were the early findings. In the link you posted concludes:

"These findings suggest that there is no suppression of mitochondrial metabolism or change in substrate preference in these two tissues despite the large changes in whole-animal metabolism seen between torpor and IBE."
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