A patient has been advised to use an over-the-counter acne product that contains benzoyl peroxide ...

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Rationale 1: It is recommended that this product be patch-tested on a small area of skin for 3 days to determine if the patient is allergic to its ingredients.
Rationale 2: Worsening of the acne is not the priority information.
Rationale 3: Rare, but potentially life-threatening, allergic reactions have occurred with use of this medication.
Rationale 4: Most products require gentle face-washing prior to application, but this is not the priority information.
Rationale 5: There is no reason to avoid aspirin when taking this medication.

Global Rationale: It is recommended that this product be patch-tested on a small area of skin for 3 days to determine if the patient is allergic to its ingredients. Rare, but potentially life-threatening, allergic reactions have occurred with use of this medication. Worsening of the acne is not the priority information. Most products require gentle face-washing prior to application, but this is not the priority information. There is no reason to avoid aspirin when taking this medication.