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Home Q & A Board Biology-Related Homework Help Medicine Pharmacology (Moderator: DelightfulMind)
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lpooziee lpooziee
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6 years ago
A male patient with hepatitis C will begin triple drug therapy with pegylated interferon alfa 2a (Pegasys), ribavirin (Ribasphere), and boceprevir (Victrelis). The patient tells the nurse that his wife is pregnant. What will the nurse tell him?
 
  a. Boceprevir is contraindicated in males whose partners are pregnant.
  b. He should use a barrier contraceptive when having sex.
  c. He should use dual drug therapy with pegylated interferon alfa and ribavirin only.
  d. This combination drug therapy is safe for him to use.
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#1
6 years ago
ANS: A
The triple combination is dangerous for pregnant women whose partners are using it, so it is contraindicated for any man whose partner is pregnant. Barrier contraceptives should be used by couples when either partner is taking the triple combination therapy to prevent pregnancy. Ribavirin is teratogenic and is not safe when a partner is pregnant. This combination is not safe for pregnant women whose partners are taking these drugs.
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