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Home Q & A Board Biology-Related Homework Help Medicine Nursing and Clinical
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normita2 normita2
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6 years ago
A patient is admitted for treatment of gout that has been refractory to treatment with allopurinol and probenecid. The patient is taking colchicine, and the prescriber orders pegloticase (Krystexxa).
 
  Before administering this drug, the nurse will expect to:
  a. administer an antihistamine and a glucocorticoid.
  b. discontinue the colchicine.
  c. increase the dose of colchicine.
  d. prepare to administer a bronchodilator if needed.
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#1
6 years ago
ANS: A
Because pegloticase poses a risk of triggering anaphylaxis, patients should be pretreated with an antihistamine and a glucocorticoid. Colchicine is indicated at the initiation of treatment with pegloticase to reduce the intensity of gout flare-ups. Bronchodilators are not indicated.
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