A nurse who works in an outpatient chemotherapy unit has received an order to administer filgrastim ...

Correct Answer: 2
Rationale 1: The white cell count will not increase rapidly, and it might not increase at all.
Rationale 2: Because antineoplastic drugs and CSFs produce opposite effects, filgrastim is not administered until at least 24 hours after a chemotherapy session.
Rationale 3: There is no increase in the risk of liver damage if these two drugs are given closely together.
Rationale 4: Both drugs have adverse reactions, but they do not potentiate each other.
Global Rationale: Because antineoplastic drugs and CSFs produce opposite effects, filgrastim is not administered until at least 24 hours after a chemotherapy session. The white cell count will not increase rapidly, and it might not increase at all. There is no increase in the risk of liver damage if these two drugs are given closely together. Both drugs have adverse reactions, but they do not potentiate each other.

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