The major difference in adverse effect profile between ACE inhibitors and ARBs is that ARBs do not ...

Correct Answer: 4
Rationale 1: ARBs can cause headaches, as can ACE inhibitors.
Rationale 2: ARBs can cause dizziness, as can ACE inhibitors.
Rationale 3: There is a risk of angioedema with ARB therapy, but it is less than that with ACE inhibitor therapy.
Rationale 4: Since ARBs do not promote accumulation of bradykinin, they do not cause a cough.
Global Rationale: Since ARBs do not promote accumulation of bradykinin, they do not cause a cough. ARBs and ACE inhibitors both can cause headaches and dizziness. There is a risk of angioedema with ARB therapy, but it is less than that with ACE inhibitor therapy.