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Wvbabie33 Wvbabie33
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6 years ago
Sulfonylureas may be added to a treatment regimen for type 2 diabetics when lifestyle modifications and metformin are insufficient to achieve target glucose levels. Sulfonylureas have been moved to Step 2 therapy because they:
 
  1. Increase endogenous insulin secretion
  2. Have a significant risk for hypoglycemia
  3. Address the insulin resistance found in type 2 diabetics
  4. Improve insulin binding to receptors
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