A client has been prescribed hydrochlorothiazide, a thiazide diuretic, to control high blood ...

Ans: A, C
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The thiazide diuretics, which are widely used to treat disorders such as hypertension, exert their action by blocking sodium reabsorption in this segment of the renal tubules, while enhancing the active reabsorption of calcium into the blood via the calciumsodium exchange transport mechanism. For this reason, thiazide diuretics have proved useful in reducing the incidence of calcium kidney stones in persons with hypercalciuria. ATPase pump maintains a low sodium concentration inside the cell by moving sodium down its concentration into the cell through special sodium channels. The pump also establishes a high concentration of potassium within the cell, causing it to diffuse down its concentration gradient across the luminal membrane into the tubular fluid.