Aspirin has a ______________ effect. (Fill in the blank)

ceiling: Aspirin has a ceiling effect whereby increasing the dose does not produce increased effects after a certain point (Figure 52). For example, an average weight individual will take 650 mg (two 325 mg tablets) of aspirin for mild to moderate pain following periodontal debridement. Let's say that this amount of aspirin does not take the individual out of pain. However, increasing the dosage to 3 or 4 tablets will not be effective in increasing the analgesic effect and may even cause more adverse side effects. Thus, if two tablets (650 mg) of aspirin are ineffective in the relief of pain, another more potent drug should be used.

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