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Home Q & A Board Biology-Related Homework Help Anatomy and Physiology
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kellyking1 kellyking1
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9 years ago
What effect would pulmonary hypertension have on the afterload experienced by the right ventricle?
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#1
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9 years ago
Hey, just did some research for you and found this:

In idiopathic pulmonary arterial hypertension (IPAH), the right ventricle (RV) is characterized by increased end-diastolic volume, change of the normal ventricular conformation tetrahedron to a crescentic trapezoid, and varying degrees of right ventricular hypertrophy (B). The right ventricle in severe idiopathic pulmonary arterial hypertension assumes a spherical shape with a greater cross-sectional area than the left ventricle (LV), which is normally larger (A). The more spherical-shaped right ventricle results in abnormal septal function that also impairs left ventricle performance. C, MR angiogram of the right ventricle and pulmonary arteries. Note the prominence of the right atrium and the right ventricle. There is heavy trabeculation of the right ventricle defining marked hypertrophy in the pulmonary hypertensive ventricle. The degrees of dilation, hypertrophy, and sphericity of the right ventricle are variable in patients with right ventricular dysfunction, but these factors are all present in idiopathic pulmonary arterial hypertension.
Source  http://circ.ahajournals.org/content/114/17/1883.full
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