Describe the stimuli that induce volumetric thirst.

Two sets of detectors initiate volumetric thirst. The first are detectors within the kidney that are sensitive to blood flow. Upon activation, these cells secrete renin, which starts a sequence of catalytic events relating to angiotensin, which in turn initiates drinking and consumption of salt. The second set of detectors is located within the atria; these detectors are sensitive to stretching of the atrial walls. These receptors report reduced atrial pressure to the brain, which initiates drinking. Evaporation will reduce the plasma compartment, leading to volumetric thirst. Other volumetric stimuli are loss of blood, vomiting, or diarrhea.

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