Direct thrombin inhibitors include lepirudin and argatroban; they:

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Direct thrombin inhibitors include lepirudin and argatroban; they:

Direct thrombin inhibitors include lepirudin and argatroban; they:

a. Require binding to antithrombin to provide their anticoagulant effect
b. Are usually monitored using the PT.
c. Are used when a patient develops heparin-induced thrombocytopenia
d. Bind all serine proteases

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