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landswithrow landswithrow
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6 years ago
Compare and contrast the five isotypes of immunoglobulins. Include structure, function, and leukocyte interaction in your answer.
 
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6 years ago
Answer: IgG: monomer with two heavy and two light chains; main antibody produced in many illnesses.
IgM: pentamer with five monomeric proteins. First antibody produced in immature B cell.
IgD: Second antibody produced in maturing B cell; similar in structure to IgG. IgA: Third antibody produced in maturing B cell; similar in structure to IgG.
IgE: Found exclusively in tissue and mucosal secretions; interacts with basophils. Involved in hypersensitivity reactions; similar in structure to IgG
Each immunoglobulin has a unique set of heavy chains: , , ,
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