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aschaffer aschaffer
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6 years ago
Three major types of RNAs are mRNA, rRNA, and tRNA. For each of the conditions below, predict the consequences in terms of the population of proteins being synthesized in a particular cell.
 
  What qualitative and quantitative changes, if any, are expected in the individual protein involved (if one is involved) and in the population of proteins in this cell?
  (a) a frameshift mutation in the heterozygous state
  (b) a deletion of a significant proportion of ribosomal genes (rDNA)
Textbook 
Essentials of Genetics

Essentials of Genetics


Edition: 9th
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6 years ago
(a) Population of proteins: Half of the protein products of that gene will be defective, and the other half will be normal. Individual protein: The protein should show multiple amino acid substitutions downstream from the point of the mutation. If a nonsense triplet is introduced, the protein will be shortened in the substituted region.
(b) Population of proteins: There would be an overall reduction in protein synthesis. Individual proteins: All of the proteins would be made in their normal form but at reduced levels.
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