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7 years ago
Describe the packing of chromatin from the 10-nm to the 30-nm fiber stage. What is the role of histones?
 
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7 years ago
10-nm chromatin fiber consists of nucleosomesbeads of DNA wound around eight core histone proteinsconnected by strands of linker DNA. The 30-nm chromatin fiber is created by the binding of histone H1, which brings the linker DNA and the nucleosomes closer together. In the solenoid model of the 30-nm fiber, the nucleosomes are brought together into a spiraling helical structure, with about six nucleosomes per complete turn.
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