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anja@phs.ae anja@phs.ae
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Posts: 480
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6 years ago
An example of a drug that may receive expedited medical approval would be:
 
  a. A drug used to treat a rare disease that affects less than 200,000 people
  b. A placebo that is administered to provide psychological control of responses
  c. A drug that may help prevent a public health threat such as HIV
  d. A drug that is being evaluated in order to determine the therapeutic index

Question 2

Which of the following statements regarding colloid statements is TRUE?
 
  a. Colloids readily diffuse into the extravascular space for fluid replacement.
  b. Colloids exert osmotic pressures that draw fluids into the vascular space for volume replacement.
  c. Colloids do not contain proteins or sugars; therefore they do not make suitable solutions for volume replacement.
  d. Colloids are inexpensive, have and long shelf-life, and are widely used among most EMS communities.

Question 3

Which sense informs a person of his or her position in space by monitoring gravity, linear acceleration, and rotation?
 
  A) Inertia B) Balance C) Equilibrium D) None of the above

Question 4

The term therapeutic index refers to:
 
  a. Ratio of a drugs lethal dose to its effective dose
  b. Amount of drug required to cause a side effect
  c. Pharmacokinetics of a drug
  d. Efficacy of a drug
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Replies
wrote...
6 years ago
Answer to q. 1

c
Rationale: a. This answer describes the definition of an orphan drug.
b. A placebo is used in testing and does not require expedited medical approval.
c. Expedited approval may be granted when a drug may be of use in treating a public health threat such as HIV.
d. The therapeutic index is obtained during preclinical phase of drug testing and does not require expedited approval.

Answer to q. 2

b
Rationale: a. Due to the large molecular size and weight, colloids remain in the vascular space.
b. Correct.
c. Colloids are generally protein-containing solutions, or have large sugar molecules (such as Dextran) and are suitable volume expanders.
d. Colloids are expensive, have a short shelf-life, and are infrequently used in the EMS community.

Answer to q. 3

C

Answer to q. 4

a

Rationale: a. The ratio of a drugs lethal dose to its effective dose determines the therapeutic index.
b. Side effects are the undesired effects of a medication.
c. Pharmacokinetics refers to the drugs movement from introduction into the system until system elimination.
d.Efficacy of a drug refers to the potential maximum therapeutic dose a drug can produce
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