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A week ago
An 80-year-old patient with chronic renal failure is admitted to the hospital with herpes simplex. The acyclovir (Zovirax) is to be administered parenterally. When preparing to administer this medication, what would the nurse expect in regard to the dose?
A)The dose is smaller due to the herpes simplex.
B)The dose is smaller based on the patient's kidney function.
C)The dose is higher in treating genital herpes.
D)The dose is higher if the creatinine is above 4.0 mg/dL.
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Abrams' Clinical Drug Therapy: Rationales for Nursing Practice
Edition: 10th
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Oral and IV acyclovir are excreted in the urine, and the dose should be decreased in patients who are older or have renal impairment. The dose is not smaller due to herpes simplex. The dose is not higher in treating genital herpes. The dose should be lower if the creatinine level is above 4.0 mg/dL.

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