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Describe the seven steps of retroviral replication.

colleen

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Describe the seven steps of retroviral replication.

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lewis

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12 years ago

Each of the seven steps is outlined in Figure 9.24 in the textbook. Once the retrovirus fuses to its host, the viral envelope is uncoated so that ssRNA is exposed. Reverse transcription then occurs to generate dsDNA that becomes integrated into the host's genome. The host's genome is transcribed into ssRNA along with the viral insert, and the viral mRNAs transcribed are encapsidated again to form more retroviruses. Progeny virions are released through a budding process within the host's cell membrane.

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