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A patient asks the healthcare professional why tissue damage occurs in acute rejection after organ ...

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A patient asks the healthcare professional why tissue damage occurs in acute rejection after organ ...

A patient asks the healthcare professional why tissue damage occurs in acute rejection after organ transplantation. What response by the professional is best?

▸ Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly attack the endothelial cells of the transplanted tissue.

▸ Circulating immune complexes are deposited in the endothelial cells of transplanted tissue, where the complement cascade lyses tissue.

▸ Receptors on natural killer cells recognize antigens on the cell surface of transplanted tissue, which releases lysosomal enzymes that destroy tissue.

▸ Antibodies coat the surface of transplanted tissue to which mast cells bind and liberate preformed chemical mediators that destroy tissue.

Textbook

Pathophysiology: The Biologic Basis of Disease in Adults and Children

Edition: 8^th

Authors: McCance, Huether

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KaylaG

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y15400211 Author

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Brilliant ツ

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You make an excellent tutor!

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Smart ... Thanks!

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