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Ija Ija
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2 years ago
A patient has been diagnosed with acute lymphocytic leukemia (ALL) and asks the healthcare professional to describe it. What description by the professional is most accurate?


▸ ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood.

▸ In ALL, immature blasts cells replace normal myelocytic cells, megakaryocytes, and erythrocytes.

▸ B cells fail to mature into plasma cells that synthesize immunoglobulins.

▸ The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene identified as BCR-ABL.
Textbook 
Pathophysiology: The Biologic Basis of Disease in Adults and Children

Pathophysiology: The Biologic Basis of Disease in Adults and Children


Edition: 8th
Authors:
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klynklyn
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