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Home Q & A Board Biology-Related Homework Help Anatomy and Physiology
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Golson Golson
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2 years ago
When diagnosed with hemolytic disease of the fetus and newborn (HDFN), why does the newborn develop hyperbilirubinemia after birth but not in utero?


▸ Excretion of unconjugated bilirubin through the placenta into the mother’s circulation is no longer possible.

▸ Hemoglobin does not breakdown into bilirubin in the intrauterine environment.

▸ The liver of the fetus is too immature to conjugate bilirubin from a lipid-soluble to water-soluble form.

▸ The destruction of erythrocytes producing bilirubin is greater after birth.
Textbook 
Pathophysiology: The Biologic Basis of Disease in Adults and Children

Pathophysiology: The Biologic Basis of Disease in Adults and Children


Edition: 8th
Authors:
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aliptsidhualiptsidhu
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2 years ago
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