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Unlike many other genetic disorders, Huntington's disease is caused by a full penetrance disease ...

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Unlike many other genetic disorders, Huntington's disease is caused by a full penetrance disease ...

Unlike many other genetic disorders, Huntington's disease is caused by a full penetrance disease allele. Full penetrance means what?

▸ The longer the allele (more triplet repeats), the more likely the disease is to occur in an individual.

▸ There are other genes that are also required for an individual to get Huntington's disease.

▸ There are environmental factors beyond age that are also required for an individual to get Huntington's disease.

▸ Individuals with a disease allele are almost certain to get Huntington's disease.

▸ Heterozygotes are just as likely to get Huntington's disease as homozygotes.

Textbook

Genetic Analysis: An Integrated Approach

Edition: 3^rd

Authors: Sanders, Bowman

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MZ Mai Author

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Thanks for your help!!

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