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SINH SINH
wrote...
2 years ago
9.   The following table lists α-globin and β-globin gene sequences for the 12 nucleotides preceding the start codon and the first nucleotide following the start codon. The data are for 16 vertebrate globin genes reported by Kozak (1987). The sequences are written from -12 to +4 with the start codon underlined.
   Gene Sequence
   -12   start +4
α-Globin Family   
Human adult   AGAGAACCCACCATGG
Human embryonic   CACCCTGCCGCCATGT
Baboon   AAAGAACCCACCATGG
Mouse adult   CAGGAAGAAACCATGG
Rabbit adult   GAAGGAACCACCATGG
Goat embryonic   TCAGCTGCCACCATGT
Duck adult   GGAGCTGCCACCATGG
Chicken embryonic   CTCTCCTGCACAATGG
β-Globin Family   
Human fetal   AGTCCAGACGCCATGG
Human embryonic   AGGCCTGGCATCATGG
Rabbit adult   AAAACAGACAGAATGG
Rabbit embryonic   AGACCAGACATCATGG
Chicken adult   CCAACCGCCGCCATGG
Chicken embryonic   CCCGCTGCCACCATGG
Xenopus adult   TCAACTTTGGCCATGG
Xenopus larval   TCTACAGCCACCATGG

Use the data in the table to
a.   Determine the consensus sequence for the 16 selected α-globin and β-globin genes.
b.   Compare the consensus sequence for these globin genes to the consensus sequence derived from the larger study of 699 vertebrate genes in Problem 8
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wrote...
2 years ago
COFFE MILL
wrote...
2 years ago Edited: 2 years ago, Tho Truong
Can you help me with the answer?
Post Merge: 2 years ago

Can you help me with the answer?
Post Merge: 2 years ago

9.   The following table lists α-globin and β-globin gene sequences for the 12 nucleotides preceding the start codon and the first nucleotide following the start codon. The data are for 16 vertebrate globin genes reported by Kozak (1987). The sequences are written from -12 to +4 with the start codon underlined.
   Gene Sequence
   -12   start +4
α-Globin Family   
Human adult   AGAGAACCCACCATGG
Human embryonic   CACCCTGCCGCCATGT
Baboon   AAAGAACCCACCATGG
Mouse adult   CAGGAAGAAACCATGG
Rabbit adult   GAAGGAACCACCATGG
Goat embryonic   TCAGCTGCCACCATGT
Duck adult   GGAGCTGCCACCATGG
Chicken embryonic   CTCTCCTGCACAATGG
β-Globin Family   
Human fetal   AGTCCAGACGCCATGG
Human embryonic   AGGCCTGGCATCATGG
Rabbit adult   AAAACAGACAGAATGG
Rabbit embryonic   AGACCAGACATCATGG
Chicken adult   CCAACCGCCGCCATGG
Chicken embryonic   CCCGCTGCCACCATGG
Xenopus adult   TCAACTTTGGCCATGG
Xenopus larval   TCTACAGCCACCATGG

Use the data in the table to
a.   Determine the consensus sequence for the 16 selected α-globin and β-globin genes.
b.   Compare the consensus sequence for these globin genes to the consensus sequence derived from the larger study of 699 vertebrate genes in Problem 8.
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