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jccruz jccruz
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The nurse is reviewing the classes of antidysrhythmic drugs. Amiodarone (Cordarone) is classified on the Vaughan Williams classification as a class III drug, which means it works by which mechanism of action?


▸ Blocking slow calcium channels

▸ Prolonging action potential duration

▸ Blocking sodium channels and affecting phase 0

▸ Decreasing spontaneous depolarization and affecting phase 4
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Pharmacology and the Nursing Process


Edition: 9th
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ricyoungricyoung
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Prolonging action potential duration

Vaughan Williams class III drugs (amiodarone, dronedarone, sotalol, ibutilide, and dofetilide) increase the action potential duration by prolonging repolarization in phase 3. The other answers are incorrect.
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