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Home Q & A Board Biology-Related Homework Help Medicine Nursing and Clinical
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colleen colleen
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12 years ago
Hashimoto's thyroiditis and Graves' disease are autoimmune diseases involving the thyroid, but Hashimoto's results in hypothyroidism (low thyroid function) whereas Graves' results in hyperthyroidism (overactive thyroid). Both diseases are characterized by antithyroid antibodies. Discuss ways in which the autoimmune responses may produce the different outcomes.
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12 years ago
In Graves' disease, the antithyroid antibodies react with receptors on the cells and stimulate their activity, leading to hyperthyroidism. In Hashimoto's disease, the antibodies targeting the thyroid cells either damage the ability of the cells to function or trigger cytotoxic attack on the cells of the thyroid, which is eventually damaged to the point of loss of function.
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