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John421 John421
wrote...
Posts: 8
Rep: 1 0
9 years ago
So when pyruvate (C3H3O3-) becomes acetyl (C2H3O) it has lost 2 oxygens (reduction), but it has also lost an electron (oxidation).

Some sources say pyruvate is oxidised to acetyl-CoA
Other sources say pyruvate is reduced to acetyl-CoA

If both oxidation and reduction happen to a molecule, is there another word you should use other than "oxidation" or "reduction" or does one take presidence over the other or something?
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wrote...
Educator
9 years ago
Yes, under aerobic conditions pyruvate is oxidised to acetyl CoA, and then undergoes complete oxidation to carbon dioxide and water. Three-carbon molecule Pyruvate is oxidised by removing hydrogen ions and electrons. NAD is reduced and travels to the electron transport chain.
John421 Author
wrote...
8 years ago
Is there a reason that it is called oxidation, when both oxidation and reduction seem to take place to pyruvate at the same time?
wrote...
Educator
8 years ago
when both oxidation and reduction seem to take place to pyruvate at the same time?

When/where does reduction take place?

As mentioned, it is NAD that is reduced and travels to the electron transport chain.
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